With the first encouraging SwissFEL experiments in structural biology delivering static and time-resolved information on compound binding it is time to discuss the recent developments and shape the future directions.

The areas to be covered by the talks are focused on the application of Serial Crystallography done at XFELs. Furthermore, recent developments on Cryo-EM as complementing method for bio-structure research will be captured. All lectures and discussions aim to answer the question: What are the benefits for drug discovery?

The contributions are structured around three sessions:

• Biostructural research at FELs

• Methods, Instrumentation and analysis tools enabling research at FELs

• Recent Developments in Cryo-Electron Microscopy

The symposium is co-organized and co-located with the BIO Division, the Photon Science Division of PSI and leadXpro AG.